The Van is a simple, yet versatile vehicle. Before the War, they were used for goods transport, with prominent users being the Vault-Tec Corporation and Lobster Grill, as well as being used by medical facilities as ambulances. Various vans on Mount Desert Island, ironically those that bear the now-defunct Lobster Grill's logo, having been taken up as residence by mutated giant Hermit crabs that use the vehicles as shells.
- At some hospitals around the Commonwealth, there are dead patients in the back. This would look to be impossible due to the van's low doors at the rear. The patient on the gurney would hit the top of the van's doors.
- Mere minutes before the bombs fell on Boston, the Vault-Tec rep parked one in front of The House of Tomorrow, the Sole Survivor's home at the time.