We're not really here. We're not really talking. It's all made-up, make-believe. We're sleeping, dreaming. The dream became a nightmare. It has to end.
”
T. "Old Lady" Dithers is one of the inhabitants of Vault 112 and part of the Tranquility Lane virtual reality simulation in Fallout 3.
Like the other inhabitants of Vault 112, Old Lady Dithers is trapped in the Tranquility Lane simulation and subject to Stanislaus Braun's whims. Considered insane by the other inhabitants, she is the only one who is aware that Tranquility Lane is a computer simulation, and that the Braun, in the guise of Betty, is torturing his subjects[1].
The terminal attached to her pod chair in Vault 112 notes that several readouts show anomalous readings and extreme levels of stress, likely either a cause or symptom of her awareness[2].
Tranquility Lane: Old Lady Dithers is the only person who is conscious about the simulation and informs the Lone Wanderer about the failsafe in the abandoned house.