Growing Up Fast - once Andy eviscerates the cake with his circular saw, Butch accosts the Lone Wanderer and demands that they gives up the sweet roll. The player has a variety of options for response: a simple dismissal, an attempt to share, a spiteful spit on the roll before giving it up, to a vicious verbal jab at his mother's drinking habits. Most responses will provoke Butch to get up and begin throwing punches at the player, which prompts Officer Gomez to intervene.
The player can eat the sweetroll before Butch has a chance of asking you for it, which will then activate a different scenario: Butch tells them that they'll "get it later".
The player can also drop the sweetroll on the ground before Butch confronts them, prompting a speech option about "throwing the sweetroll away".
Planting the sweetroll on Butch will result in the above two options appearing.
The sweetroll is a staple for many of Bethesda's games, and is sort of an ongoing joke. The sweetroll itself originated in The Elder Scrolls: Arena where, at the beginning of the game, one of the class-determining questions is: "While in town the baker gives you a sweetroll. Delighted you take it into an ally to enjoy, only to be intercepted by a gang of three kids your age. The leader demands the sweetroll, or else he and his friends will beat you and take it. Do you: ..."
The model for sweetrolls originate from The Elder Scrolls IV: Oblivion.