This signal is first discovered when the Sole Survivor activates the relay dishes at relay tower 0DB-521. The source of the signal can then be tracked the wreckage of Skylanes Flight 1665. It an deactivated by flipping the circuit breaker in the aircraft's storage compartment, accessible through a hatch located between some of the last rows of seats at port side.
Skylanes one six six five, twenty miles out.
Roger Skylanes one six six five, traffic short final. Cleared to land on runway one eight left.
Copy, one eight left. Coming in at four seven five knots. That's four seven...hang on control.
Uh...fire in left engine. Losing power in left engine.
Okay, lets put it out. Left engine to idle.
Shit. Still losing power.
That's it, no power in left engine. Boston Center, Skylanes one six six five declaring an emergency. Left engine failure. We're out fifteen three at this time.
Copy that Skylanes one six six five, request emergency landing. Clearing runway one eight left. Can you make it?
Uh...that's a negative Boston center, losing altitude too quickly. We will not make it to runway.
One six six five, say again?
We're going down. I repeat, we are going down!
Section needed (How this contradicts the Skylanes flight 1665 final transmission)
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The Skylanes 1665 mayday appears only in Fallout 4.