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The Vault - Fallout Wiki
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For the character from the Fallout Tactics demo, see Psycho (character).
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This is a lore summary, presenting intradiegetic or in-universe information about the subject. For game characteristics and similar data, consult the table on the right.
Game-specific articles
Fallout 2Psycho
Fallout 3Psycho
FO: New VegasPsycho
Fallout 4Psycho
Psycho Jet
Fallout 76Psycho
FO TacticsPsycho
Fallout: BoSPsycho

Psycho, colloquially termed "angry juice" and "the big red one",[1] is a military-grade, performance-enhancing drug in all Fallout games.


A military-grade psychosis-inducing amphetamine, Psycho is provided in a unique delivery system that mixes strange chemicals of military origin immediately prior to injection.[2][3][4] The drug saw its inception in the laboratories of a research division operating under the authority of General Constantine Chase, who used methamphetamine as basis, making the result drug almost like, but legally distinct from it.[5] It entered combat use during the final stages of the Anchorage Reclamation, to reduce the impact of attrition on U.S. forces deployed to the Alaskan front. Its deployment was authorized by General and his chief medical officer, Dr. Adrienn Adami, despite the clinical trials being incomplete at the time.[6]

Its primary effect is an increase in damage resistance and dampening of higher brain functions, intended to create tough shock troops for human-wave assaults. The caveat is that the dampening effect also makes the soldiers hard to control.[7] Some variants of Psycho, based around similar chemicals, also increase combat performance by speeding up reflexes and bodily functions to allow the soldiers to deal more damage, though said variant precluded the damage resistance boost.[8] Both cause them to be particularly jumpy and aggressive.[9]

Due to the rushed nature of the drug development and deployment, numerous side effects manifest as a result of Psycho usage. Chief among these is that the stimulant can cause users with weak hearts to suffer a fatal heart attack.[10][11] Long term effects include dementia, psychosis,[6] elevated levels of aggression, and general agitation. Addiction aggravates the adverse symptoms.[12]



Chem psycho.png
Gameplay articles:

The basic variants of Psycho are highly addictive and exist in two classes: one that increases damage resistance and one that increases damage dealt in combat. They are potent combat drugs should be used in moderation and fetch a high price on the market.


FO3 psycho.png
Gameplay article:

A next-generation chem is a cocktail of Psycho and Med-X that combines the effects of both drugs. It is just as addictive as the original variants, but offers far superior performance.

See also


  1. The Courier: "Sgt. McCredie asked me to talk to you about getting your squad in shape."
    Razz: "Yo, I'll tell you what this squad needs. A healthy dose of angry juice."
    The Courier: "Angry... juice?"
    Razz: "Psycho! The big red one! I used to run with the Fiends, I still got the hookups. Smuggle some in and you'll see an improvement."
    (Razz's dialogue)
  2. Fallout and Fallout 2 item description: "{11000}{}{Psycho}
    {11001}{}{An unique delivery system filled with strange and unknown chemicals of probably military origin. It is supposed to increase the combat potential of a soldier.}"
    (PRO ITEM.MSG (Fallout), PRO ITEM.MSG (Fallout 2))
  3. Fallout Tactics: Brotherhood of Steel item description: "name_psychoChem = {Psycho}
    desc_psychoChem = {An unique delivery system filled with strange and unknown chemicals of probably military origin. It is supposed to increase the combat potential of a soldier.}"
  4. Fallout 4 loading screen hints: "Originally developed by the United States military to increase soldiers' combat effectiveness, Psycho grants the user increased Damage output and Damage Resistance for a limited period of time."
  5. Razz: "{Tripping out on a drug almost like but legally distinct from meth}Ha ha, fuck me, Jack's shit is still the best!"
  6. 6.0 6.1 Holotape - Psycho: "Physician's Log, Doctor Adrienn Adami, United States Army, Anchorage, Alaska forward base.
    Considering what's at stake, General Chase and I both feel the chem codenamed "Psycho" can be of significant use during this operation.
    I've read the early clinical trials, and there are certainly some possible side effects -- dementia, psychotic aggression. And of course addiction.
    But the adverse effects do seem limited. Okay, I do realize the chem was developed by Chase's R&D division, but if the thing works it works.
    Can we really afford to be picky at this point? Some of these groundpounders have family in Anchorage. I'll give them any boost I damn well can.
    I just hope my Hippocratic Oath is still speaking to me when this whole mess is over with..."
  7. Fallout 2 Official Strategies & Secrets p.75: "The drug was developed specifically for military use. It increases a soldier's damage resistance, and its dampening effect on higher brain functions makes for tough, but uncontrollable, troops. This drug was very popular for human-wave assaults. Take it just before a difficult combat, and then go someplace safe to sit out the aftereffects."
  8. Fallout 3 and Fallout: New Vegas drug effects.
  9. Ricky: "Oh man, yeah! Trigger finger is feeling itch-ay! Come on, assholes! Show yourselves and Deadeye Ricky'll blow your fucking heads off!"
    (Ricky's dialogue)
  10. The Courier: "Add a little Psycho to his Jet, and he'd have a heart attack."
    Dennis Crocker: "[SUCCEEDED] Remind me never to get on your bad side. If that's true, then yes, that would be a suitable way to get rid of him. However, it would involve gaining access to his personal drug stash and tampering with it unseen, which might pose a challenge."
    (Dennis Crocker's dialogue)
  11. Big Jesus Mordino and John Cassidy, both of whom have bad hearts, will die if they use Psycho.
  12. The Courier: "Unwarranted hostility and general agitation. How long have you been a Psycho addict?"
    Ricky: "[SUCCEEDED] Hey hey hey! Fuck you! I didn't say nothing about using Psycho!"
    (Ricky's dialogue)