Moonshine is the strongest alcoholic drink in the game. Though it bears the same 10% addiction rate as weaker alcoholic drinks, such as whiskey, it has doubled the effect on the same SPECIAL attributes - increasing Charisma and Strength by two, while reducing Intelligence by two.
Beer might be a preferable alternative, considering its 5% addiction rate and the copious amounts of it, scattered throughout the Capital Wasteland, but the effects of beer, as with other alcoholic drinks, will not stack. This means drinking more than one beer will not change your stats any more than one would. Moonshine can still be consumed and its effects will "overwrite" the effects of other alcoholic drinks. However, beer has a value of only 2, but moonshine has a value of 50; moonshine may be better suited to selling, rather than drinking.
Behind the scenes
Moonshine is a common term for home-distilled alcohol, especially in places where this practice is illegal. The name stems from the American Prohibition era, where homemade stills were often operated under the light of the moon.