|For an overview of Nuka-Cola soda throughout the Fallout series, see Nuka-Cola.|
Introduced only a few years after the Nuka-Cola Corporation was founded, Nuka-Cola Orange was an instant success to the market along with the other fruit flavors of Nuka-Grape and Nuka-Cherry. However, these flavors were only distributed on the East Coast of the United States.
- Created by chilling a regular Orange using Drinking Buddy.
- Nuka-World loading screen hints: "Nuka-Cola introduced fruit-flavored beverages such as Nuka-Cherry, Nuka-Grape and Nuka-Orange only a few short years after the corporation was founded. They were an instant success."
- World of Refreshment tour: "While out here on the east coast, folks delight in the refreshment of an ice-cold Nuka-Grape, Nuka-Orange, or Nuka-Cherry. And be on the lookout for our special pre-release shipments of Nuka-Cola Quantum coming soon to your favorite grocer or restaurant!"