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This page lists all mutations in Fallout 76.
  • The content is not described in full detail on this page. For details, please see the respective articles.
  • For mutations in other Fallout games, please see "Mutation".
  • For an overview of Fallout 76 content, please refer to "Fallout 76".
 
Gametitle-F76
Gametitle-F76

Overview[]

Fallout 76 alters the way radiation works: Instead of just limiting SPECIAL stats or max health, it allows the player character to develop various mutations, which act like traits in other games in the series: They give a mixture of powerful positive and negative effects. The Class Freak perk will reduce the negative effects of a mutation by up to 75%, while Strange in Numbers will grant a 25% increase to the positive effect if teammates are also mutated.

It is also possible to acquire multiple mutations at the same time, including all 19 that are currently available (the sole exception is Carnivore and Herbivore which lock each other from being acquired). However, to have all 19 active is wildly disproportionate to any playstyle and is recommended to pursue mutations that synergize with each other.

Acquisition[]

Whenever a player takes Radiation damage, they have a chance to gain a Mutation, equivalent to 5% per 5 points of radiation damage. Players cannot gain Mutations if they are below Level 5.

Serums[]

Serums are consumable items that will grant a specific Mutation as soon as the player uses it, and temporarily suppress the negative effects of the Mutation and increase the positive effects. If the player already has the mutation, the serum will still temporarily suppress the negative effects of the Mutation and increase the positive effects. All serums and their recipes are sold by MODUS at the Whitespring Bunker Science Wing terminal. Recipes for the serums can also be purchased from MODUS but have a steep price of 24000 caps per recipe.

Removal[]

Mutations are semi-permanent. Every time the player uses RadAway or a Decontamination Shower, there is a chance that a Mutation will be removed. They can keep using RadAway for more attempts to remove a Mutation. The Starched Genes perk allows for locking mutations, as it reduces/eliminates both the chance of becoming mutated and their removal chance by RadAway. These are the only ways present to remove mutations. Mutations cannot be removed through death. However, a percentage of rads is removed through each death, so it's possible to decontaminate oneself through multiple deaths if the Starched Genes is not yet acquired.

Suppression[]

Even with the Starched Genes perk, a Mutations' effects can be suppressed for a time with the use Rad-X. The suppression lasts for approximately 10 minutes (1 hour in-game). To avoid the suppression effects of Rad-X, the diluted version can be used as it offer the benefits of it without the suppression effect.

List[]

Mutation Positive effects Negative effects Crafting
Adrenal Reaction Increased weapon damage and health regeneration at low hit points Reduced maximum hit points
Components
Bird Bones +4 Agility. Falling from heights is slower and safer. -4 Strength.
Components
Carnivore Meat provides double the benefits and no diseases. Cannot eat vegetables.
Components
Chameleon While crouched, unarmoured, and stationary; gain invisibility. Requires the player to be effectively naked.
Components
Eagle Eyes Critical damage +25%.

+4 Perception.

-4 Strength.
Components
Egg Head +6 Intelligence. -3 Strength.

-3 Endurance.

Components
Electrically Charged 40% Chance to shock melee attackers upon being hit. Shock deals energy damage to player
Components
1 Oil
Empath -25% damage taken by teammates. +33% damage taken by player.
Components
Grounded +100 Energy Resistance. -50% Energy damage.
Components
Healing Factor Health regeneration +300%. Chem effects -55%.
Components
Herbivore Vegetables provide double the benefits and no diseases. Cannot eat meat.
Components
Herd Mentality +2 to all SPECIAL stats when grouped. -2 to all SPECIAL stats when solo.
Components
1 Oil
Marsupial Carry weight +20, improved jump height. -4 Intelligence.
Components
1 Oil
Plague Walker Poison aura scaling with the player's diseases Affects everyone, even friendlies
Components
1 Oil
Scaly Skin +50 damage and energy resistance. -50 AP.
Components
1 Oil
Speed Demon +20% movement speed and reload speed. Increased Hunger and Thirst accumulation
Components
Talons Unarmed attacks deal 25% more damage and cause bleeding. -4 Agility
Components
Twisted Muscles +25% melee damage. Better chance to cripple enemy limbs. -50% gun accuracy.
Components
Unstable Isotope 10% chance to release a radiation blast when struck in melee. The radiation blast irradiates the player
Components
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