The Vault - Fallout Wiki

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The Vault - Fallout Wiki
This page lists all diseases in Fallout 76.
  • The content is not described in full detail on this page. For details, please see the respective articles.
  • For diseases in other Fallout games, please see "Disease".
  • For an overview of Fallout 76 content, please refer to "Fallout 76".

General information

Diseases are temporary status effects that can be contracted by the player. Unlike mutations, they provide no positive effects and only negative ones. Diseases can be either cured by using a Disease Cure or waiting until they expire.

Diseases are contracted by:

  • Sleeping on the ground in bedrolls or on mattresses.
  • Coming into contact with diseased critters.
  • Swimming in contaminated, irradiated waters.
  • Being exposed to toxic air (e.g. in The Mire) without a gas mask on.


Mutation Duration Negative effects
Blight 30 minutes -1 to all S.P.E.C.I.A.L stats
Bloodworms 15 minutes Take 25% more damage
Boneworms Take 50% more damage
Buzz Brain -2 intelligence
Dysentery 15 minutes Periodic water loss
Fever Claw 25% damage with melee weapons
Flap Limb 30 minutes -2 strength
Glowing Pustules Bleed radiation from wounds
Heat Flashes -2 endurance
Jelly Fingers +50% AP Cost in VATS
Lock Joint
Needle Spine -10 carry weight
Parasites Periodic food loss
Rad Worms 45 minutes Increases radiation damage taken by 50%
Rattle Hands -25% damage with ranged weapons
Shell Shock Action point drain from wounds
Sludge Lung
Snot Ear 15 minutes -2 Perception
Swamp Gas -2 charisma
Swamp Itch 15 minutes -2 Agility
Weeping Sores Bleed from wounds
Woopsies -2 luck