Attacks with the gauntlet disregard damage resistance from armor. Thus, while it appears to be equal in damage to the power fist, it is actually far superior against armored foes due to its armor piercing ability and x5 critical chance multiplier. This means that it can tear Tesla armoredEnclave soldiers apart as easily as it can kill unprotected enemies.
With 10 Luck and Ninja, you will always score a critical hit, thus making it even more powerful than the Shishkebab against armored foes.
Oddly enough, if you compare the size of a deathclaw gauntlet with that of a deathclaw's hand, the gauntlet appears to be much smaller.
Though an unarmed weapon, this weapon has the same quick-select symbol and makes the same sound as a melee weapon when equipped.
The deathclaw gauntlet weighs twice as much as all of the components used to craft it; deathclaw hand (1 lb), medical brace (2 lbs), leather belt (1 lb), and wonderglue (1 lb), yet deathclaw gauntlet is 10 lbs.
When the hand is taken from a corpse of a deathclaw, somehow the deathclaw still has both hands.
The deathclaw hand in the finished model of the weapon appears to have a lighter skin color than the normal deathclaw hand.
The deathclaw gauntlet heavily resembles the redesigned glove used by Freddy Krueger in the movie A New Nightmare.
When blocking with this weapon in first-person, the gauntlet fills up the whole screen.