Brimstone squad is the best of the best. They're comprised of 8 battle-hardened Paladins, and the high general of the Brotherhood himself. However, that didn't stop them from being slaughtered by the mutant ambush in St. Louis, where the mutant armies destroyed them and took the general hostage. The only surviving member was Burke.
Interactions with the player
The Warrior interacts with the squad's leader, General Barnaky, throughout the game. During the mission in St. Louis, the player encounters the last survivor of the squad, Burke.