Revelation 21:6

Revelation 21:6 is a paper note in Fallout 3. It is added to the Lone Wanderer's PIP-Boy 3000 when first talking to their father, James when first entering the Jefferson Memorial Rotunda – Project Purity – during the quest The Waters of Life.

Background
Revelation 21:6 is a passage in the New Testament of the Christian Bible, appearing in the Book of Revelation.

It is mentioned several times during the course of Fallout 3 by James, the Lone Wanderer's father, who says it was the favorite of Catherine, his deceased wife and mother of the Lone Wanderer. The Greek letters alpha and omega are essentially the same as the Latin letters A and Z, implying that God is the first and last of all things. They are also a recurring motif in Christian imagery and iconography.

As applied to the post-apocalyptic setting of Fallout, the introduction of 21:6 in the first tutorial quest can be seen as a foreshadowing of Project Purity, an attempt to purify all the irradiated water in the Tidal Basin by the Jefferson Memorial. After being reunited with James, the player learns that this passage was the inspiration for the project. In the game's climax, the code "216" is used to activate the water purifier. It might also, depending on what path of Karma the player takes, be a prophecy of the Lone Wanderer's transformation into the new Wasteland Savior by his or her final act of self-sacrifice.